Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model

Journal article

Open access

Peer reviewed

Journal of experimental & clinical cancer research, Vol.35(1), pp.74-74

06/05/2016

PMCID: PMC4859966

PMID: 27154307

Abstract

Dual gene virotherapy

Hepatocellular carcinoma

Interleukin-12

Oncolytic adenoviruses

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

url

https://doi.org/10.1186/s13046-016-0353-8View

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Title: Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model
Creators - without role: Adel Galal El-Shemi - Umm al-Qura University
Ahmad Mohammed Ashshi - Umm al-Qura University
Youjin Na - Hanyang University
Yan Li - Yonsei University
Mohammed Basalamah - Umm al-Qura University
Faisal Ahmad Al-Allaf - Umm al-Qura University
Eonju Oh - Hanyang University
Bo-Kyeong Jung - Hanyang University
Chae-Ok Yun - Hanyang University
Publication Details: Journal of experimental & clinical cancer research, Vol.35(1), pp.74-74
Publisher: BioMed Central
Grant note: 11-MED2065-10 / ; Award Number (11-MED2065-10). / ;
Identifiers: 9930969808331
Academic Unit: Umm Al Qura University
Language: English
Resource Type: Journal article