Sign in
Back
Complete congenital anterior pituitary insufficiency and syndrome of inapropriate antidiuretic hormone secretion: a rare association in children
Journal article   Peer reviewed

Complete congenital anterior pituitary insufficiency and syndrome of inapropriate antidiuretic hormone secretion: a rare association in children

Mohammed Alharbi and Michel Polak
Journal of pediatric endocrinology & metabolism : JPEM, Vol.19(12), pp.1445-1450
01/12/2006
DOI: https://doi.org/10.1515/JPEM.2006.19.12.1445
PMID: 17252698

Abstract

Adolescent Child, Preschool Female Fluid Therapy Hormone Replacement Therapy Humans Hyponatremia - diagnosis Hyponatremia - etiology Hyponatremia - therapy Hypopituitarism - complications Hypopituitarism - drug therapy Hypopituitarism - metabolism Hypopituitarism - pathology Inappropriate ADH Syndrome - etiology Inappropriate ADH Syndrome - metabolism Inappropriate ADH Syndrome - pathology Inappropriate ADH Syndrome - therapy Magnetic Resonance Imaging Male Pituitary Gland, Anterior - metabolism Pituitary Gland, Anterior - pathology Treatment Outcome Vasopressins - metabolism
Two children with complete congenital anterior hypopituitarism developed hyponatremia; inappropriate secretion of antidiuretic hormone was documented despite adequate hormonal replacement therapy. These cases show that congenital hypopituitarism can be associated with SIADH in children later than the neonatal period, despite adequate replacement therapy.

Metrics

1 Record Views

Details