Abstract
Complexes of nalidixic acid with Ca(II), Mg(II), Zn(II), Fe(III), and VO(II) ions, have been synthesized and characterized by means of microanalysis, conductance, IR, NMR and UV-Vis spectroscopy and thermogravimetric (TGA/DTG and DTA) measurements. The ligand coordinates in a bidentate mode via one carboxylate oxygen atom and the oxygen atom of the pyridine carbonyl group. The kinetic thermodynamic parameters such as: activation energy
E
*, Δ
H
*, Δ
S
*, and Δ
G
* have been estimated using Coats and Redfern as well as Horowitz-Metzger equations. Antimicrobial activity of the obtained complexes against some kinds of bacteria and fungi has been evaluated.