Computational and Preclinical Analysis of 2-(4-Methyl)benzylidene-4,7-dimethyl Indan-1-one (IPX-18): A Novel Arylidene Indanone Small Molecule with Anti-Inflammatory Activity via NF-κB and Nrf2 Signaling

Journal article

Open access

Peer reviewed

Biomedicines, Vol.11(3), p.716

27/02/2023

PMID: 36979695

Abstract

akt

arylidene

basophils

inflammation

mast cells

neutrophils

NF-κB

Nrf2

RBL-2H3

url

https://doi.org/10.3390/biomedicines11030716View

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Title: Computational and Preclinical Analysis of 2-(4-Methyl)benzylidene-4,7-dimethyl Indan-1-one (IPX-18): A Novel Arylidene Indanone Small Molecule with Anti-Inflammatory Activity via NF-κB and Nrf2 Signaling
Creators - without role: Reem M. Gahtani - King Khalid University
Ahmad Shaikh - King Khalid University
Hossam Kamli - King Khalid University
Publication Details: Biomedicines, Vol.11(3), p.716
Publisher: MDPI
Grant note: RGP.1/191/43 / King Khalid University
Identifiers: 9923363608331
Academic Unit: King Khalid University
Language: English
Resource Type: Journal article