Abstract
A simple titrimetric method was developed for the determination of some drugs acting on the central nervous system, namely, phenobarbital, thiopental sodium and the hydrochloride salts of chlorpromazine, promazine, trifluoperazine and pyritinol. The method is based on titrating these drugs using either sodium hydroxide, mercury(II) chloride or silver nitrate. The end point was located conductimetrically. The proposed method was successfully applied to the determination of the studied compounds in some pharmaceutical preparations and the results obtained were in agreement with those obtained using official or reference methods.