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Configuration of Trimethylsilyl Derivatives of 2-Oxo-carbonic Acids
Journal article   Peer reviewed

Configuration of Trimethylsilyl Derivatives of 2-Oxo-carbonic Acids

Heinrich Binder and Ahmed A. Ashy
Journal of chromatographic science, Vol.22(12), pp.536-537
12/1984

Abstract

The formation of two trimethylsilyl (TMS) groups is observed when the Ca-salts of some biologically important 2-oxo-carbonic acids are silylated. E/Z isomers that are separable by gas chromatography are thereby formed. The configuration of these TMS derivatives is explained using gas chromatography, mass spectrometry, and nuclear magnetic resonance spectrometry.

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