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Conjugate addition of indoles and thiols with electron-deficient olefins catalyzed by Bi(OTf) 3
Journal article   Peer reviewed

Conjugate addition of indoles and thiols with electron-deficient olefins catalyzed by Bi(OTf) 3

M.Mujahid Alam, Ravi Varala and Srinivas R. Adapa
Tetrahedron letters, Vol.44(27), pp.5115-5119
30/06/2003

Abstract

addition reactions Bi(OTf) 3 indoles thiols α,β-unsaturated compounds
Conjugate addition of indoles and thiols with a variety of electron-deficient olefins mediated by a catalytic amount of Bi(OTf) 3 at ambient temperature to afford the corresponding Michael adducts in good to excellent yields with high selectivity is reported. Graphic

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