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Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature Review
Journal article   Open access  Peer reviewed

Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature Review

Maram Al-Banyan, Abdulhadi Alqahtam, Farrukh Sheikh, Agha M. Rehan Khaliq, Hasan Al Rayes, Ashraf Al-Tarifi, Bandar Al-Saud and Rand K. Arnaout
American journal of infectious diseases, Vol.15(1), pp.24-28
01/01/2019
DOI: https://doi.org/10.3844/ajidsp.2019.24.28

Abstract

Infectious Diseases Life Sciences & Biomedicine Science & Technology
Hyper-IgM syndrome (HIGM) due to CD40 deficiency is a very rare form of combined immunodeficiency with increased susceptibility to opportunistic infections. Cryptococcus is an opportunistic infection usually affecting immunocompromised individuals. This is the first report to describe a patient with HIGM due to CD40 deficiency presenting with meningoencephalitis secondary to Cryptococcus infection.
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https://doi.org/10.3844/ajidsp.2019.24.28View
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