Abstract
The catalytic property of a mononuclear Cu(II) salen complex in Chan-Lam coupling reaction with phenyl boronic acid at room temperature is reported. The studied complex is found to be potential catalyst in the preparation of carbon-heteroatom bonds with excellent yields. The studied Cu(II) salen complex is monoclinic with cell parameters, a = 9.6807(5) (alpha 90 degrees), (b = 17.2504(8) (beta 112.429 (2), c = 11.1403 (6) (gamma = 90 degrees), and has distorted square planar environment around Cu(II) ion. Furthermore, there is no pi center dot center dot center dot pi at interactions in the reported complex due to large distance between the centroid of aromatic rings.
In addition, DNA binding study of Cu(II) salen complex by fluorescence and absorption spectroscopy is also reported. Moreover, the reported Cu(II) salen complex exhibits significant anticancer activity against MCF-7 cancer cell lines, and displays potential antimicrobial biofilm activity against P. aeruginosa, suggesting antimicrobial biofilm an important tool for suppression of resistant infections caused by P. aeruginosa. (C) 2016 Elsevier B.V. All rights reserved.