Abstract
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•Cyclocarbonylation-iodination of arynes.•Ring expansion.•1,2-migration.•One-Pot, three-component, room temperature reaction.•Good yields and Substrate scope.
A simple, three-component, one-pot, room-temperature reaction of cyclocarbonylation-iodination is developed from terminal alkynes, ketones, and ICl. The reaction proceeds through the formation of 3°-propargyl alcohols and a subsequent 1,2-shift lead to the formation of β-iodo-α,β-unsaturated cyclic and acyclic ketones in good yields. In the case of cyclic ketones, the products are obtained with ring expansion.