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Cyclooxygenase-2 169CG and 8473TC gene polymorphisms and prostaglandin E2 level in breast cancer: A case-control study
Journal article   Peer reviewed

Cyclooxygenase-2 169CG and 8473TC gene polymorphisms and prostaglandin E2 level in breast cancer: A case-control study

M.S Fawzy, N.M.M Aly, S.M Shalaby, W.H El-Sawy and R.S Abdul-Maksoud
Gene, Vol.527(2), p.601
25/09/2013
DOI: https://doi.org/10.1016/j.gene.2013.06.007

Abstract

Breast cancer Cancer COX-2 inhibitors Genes Genetic aspects Genetic research Oncology, Experimental Prostaglandins E
Byline: M.S. Fawzy, N.M.M. Aly, S.M. Shalaby, W.H. El-Sawy, R.S. Abdul-Maksoud Cyclooxygenase 2 (COX-2) with the resulting prostaglandin E2 (PGE2) is linked to increased risk of human breast cancer (BC). The aim of this study was to determine COX-2 169CG and 8473TC gene polymorphisms and PGE2 level at various stages of BC clarifying the role of COX-2 gene polymorphism and PGE2 in relation to BC. Article History: Accepted 4 June 2013

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