Abstract
Clinically significant cytomegalovirus cholangitis is frequently observed in patients with AIDS, but is less common in other groups of immunocompromised patients. The present article reports a case involving a 65-year-old man, seven years post-renal transplant, who presented with abdominal pain, weight loss and loss of appetite with elevated levels of alkaline phosphatase and gamma glutamyl transferase. Endoscopic retrograde cholangiopancreatography identified a papillary mass and a distal common bile duct stricture. Histopathological analysis of papillary mass revealed a cytomegalovirus infection. The patient improved clinically following treatment with valganciclovir.