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DABCO-CATALYZED GREEN SYNTHESIS OF THIAZOLE AND 1,3-THIAZINE DERIVATIVES LINKED TO BENZOFURAN
Journal article   Peer reviewed

DABCO-CATALYZED GREEN SYNTHESIS OF THIAZOLE AND 1,3-THIAZINE DERIVATIVES LINKED TO BENZOFURAN

Sobhi M. Gomha, Mohamed G. Badrey and Wael A. A. Arafa
Heterocycles, Vol.92(8), pp.1450-1461
01/08/2016

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
An eco-friendly and simple procedure for the reaction of 2-(1-(benzofuran-2-yl)ethylidene)hydrazinecarbothioamide with arylidenemalononitriles and hydrazonoyl halides catalyzed by using sterically hindered organic base, 1,4-diazabicyclo[2.2.2]octane (DABCO) was described. This new protocol has the advantage of good yields and short reaction times. The structure of the newly synthesized compounds was elucidated via elemental analyses and spectral data.

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