Abstract
Introduction: Systemic lupus erythematosus (SLE) is considered a chronic autoimmune disease that mainly affects females. It is recognized by a wide spectrum of clinical conditions, but, its course and organ involvement are unpredictable. Though over the last years an enhancement in survival for SLE patients has been found, pathogenic mechanisms causing this disease are under investigation. Comorbidities, due to both disease and treatment, as well as multiple aspects of SLE, are under intensive investigation. There are many reviews and studies on SLE focusing on pathogenesis, clinical and laboratory features, as well as current and new therapeutic strategies published over the last year.Aim of work: In this review, we will discuss Diagnosis and management of Systemic lupus erythematosus
Methodology: We did a systematic search for Diagnosis and management of Systemic lupus erythematosus using PubMed search engine (http://www.ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com). All relevant studies were retrieved and discussed. We only included full articles.
Conclusions: Systemic lupus erythematosus (SLE) is considered a chronic autoimmune disease that mainly affects females. It is recognized by a wide spectrum of clinical conditions, but, its course and organ involvement are unpredictable. Though over the last years an enhancement in survival for SLE patients has been found, pathogenic mechanisms causing this disease are under investigation. But a major knowledge in the SLE pathogenesis and consequently the implication of therapeutic strategies are still needed to better prevent and cure SLE.