Abstract
Drug-induced hypersensitivity or drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe skin adverse drug reaction induced by a limited number of drugs. DRESS syndrome occurs within 1 to 8 weeks of the treatment. We report a 36-year-old man who presented a DRESS syndrome associated with carbamazepine and cytomegalovirus reactivation. All symptoms resolved after drug withdrawal and treatment with corticoids and ganciclovir. The DRESS syndrome features, pathophysiology, and treatment are discussed based on the available literature.