Abstract
•DL image reconstruction of axial T2 TSE imaging (T2DL) provides 65 % acquisition time reduction.•T2DL allows high resolution MRI of the prostate in axial plane within 1:38 min.•T2DL was rated superior regarding image quality and lesion detectability.
To introduce a novel deep learning (DL) T2-weighted TSE imaging (T2DL) sequence in prostate MRI and investigate its impact on examination time, image quality, diagnostic confidence, and PI-RADS classification compared to standard T2-weighted TSE imaging (T2S).
Thirty patients who underwent multiparametric MRI (mpMRI) of the prostate due to suspicion of prostatic cancer were included in this retrospective study. Standard sequences were acquired consisting of T1- and T2-weighted imaging and diffusion-weighted imaging as well as the novel T2DL. Axial acquisition time of T2S was 4:37 min compared to 1:38 min of T2DL. Two radiologists independently evaluated all imaging datasets in a blinded reading regarding image quality, lesion detectability, and diagnostic confidence using a Likert-scale ranging from 1 to 4 with 4 being the best. T2 score as well as PI-RADS score were obtained for the most malignant lesion.
Mean patient age was 65 ± 11 years. Noise levels and overall image quality were rated significantly superior by both readers with a median of 4 in T2DL compared to a median of 3 in T2S (all p < 0.001). Lesion detectability was also rated higher in T2DL by both readers with a median of 4 versus a median of 3 in T2S (p = 0.005 and <0.001, respectively). There was no difference regarding PI-RADS scoring between T2DL and T2S affecting patient management.
Deep learning axial T2w TSE imaging of the prostate is feasible with reduction of examination time of 65 % compared to standard imaging and improvement of image quality and lesion detectability.