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Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2hydroperoxy-4-hydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo[3.1.0] hexane-1-carboxamide
Journal article   Open access

Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2hydroperoxy-4-hydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo[3.1.0] hexane-1-carboxamide

Muhammad Ashfaq, Muhammad Nawaz Tahir, Islam Ullah Khan, Mohammad S. Iqbal and Muhammad Nadeem Arshad
Acta crystallographica. Section E, Structure reports online, Vol.64, pp.O1548-U2801
01/08/2008
DOI: https://doi.org/10.1107/S1600536808022265
PMID: 21203252

Abstract

Crystallography Physical Sciences Science & Technology
The degradation of atorvastatin calcium in methanol and hydrogen peroxide results in the crystallization of the title compound, C26H24FNO6, which shows several differences compared with the starting compound. In the crystal structure of the title compound, intra- and intermolecular hydrogen bonding is found.
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https://doi.org/10.1107/S1600536808022265View
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