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Dehydroconicasterol and Aurantoic Acid, a Chlorinated Polyene Derivative, from the Indonesian Sponge Theonella swinhoei
Journal article   Peer reviewed

Dehydroconicasterol and Aurantoic Acid, a Chlorinated Polyene Derivative, from the Indonesian Sponge Theonella swinhoei

Rihab F. Angawi, Barbara Calcinai, Carlo Cerrano, Henny Adeleida Dien, Ernesto Fattorusso, Fernando Scala and Orazio Taglialatela-Scafati
Journal of natural products (Washington, D.C.), Vol.72(12), pp.2195-2198
28/12/2009
PMID: 19961178

Abstract

Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Plant Sciences Science & Technology
The chlorinated polyene aurantoic acid (1) and the 4-methylene sterol dehydroconicasterol (2) were isolated from the Indonesian sponge Theonella swinhoei, and their structures were elucidated by interpretation of spectroscopic data. Aurantoic acid is a unique member in the class of naturally occurring conjugated polyene derivatives, while dehydroconicasterol is the likely biogenetic precursor of the major Theonella 4-methylene sterols.

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