Abstract
In this study, bio-inspired computing is presented for finding an approximate solution of governing system represents the dynamics of the Heart Beat Model (HBM) using feed-forward Artificial Neural Networks (ANNs), optimized with Genetic Algorithms (GAs) hybridized with Interiort-Point Algorithm (IPA). The modeling of the system is performed with ANNs by defining an unsupervised error function and optimization of unknown weights are carried out with GA-IPA; in which, GAs is used as an effective global search method and IPA for rapid local convergence. Design scheme is applied to study the dynamics of HBM by taking different values for perturbation factor, tension factor in the muscle fiber and the length of the muscle fiber in the diastolic state. A large number of simulations are performed for the proposed scheme to determine its effectiveness and reliability through different performance indices based on mean absolute deviation, Nash-Sutcliffe efficiency, and Thiel's inequality coefficient. (c) 2016 Elsevier B.V. All rights reserved.