Design, synthesis, and biological evaluation of novel N4-substituted sulfonamides: acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors

Journal article

Open access

Peer reviewed

BMC chemistry, Vol.13(1)

11/07/2019

PMCID: PMC6661844

PMID: 31384838

Abstract

Acetamides

Anticancer

Antimicrobial

DHFR inhibitors

Molecular docking

Structure–activity relationship (SAR)

Sulfonamide

url

https://doi.org/10.1186/s13065-019-0603-xView

Published (Version of record) Open

1 Record Views

Title: Design, synthesis, and biological evaluation of novel N4-substituted sulfonamides: acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors
Creators - without role: Essam M. Hussein - Assiut University
Munirah M. Al-Rooqi - Umm al-Qura University
Shimaa M. Abd El-Galil - Nacr City, Cairo, Egypt
Saleh A. Ahmed - Assiut University
Publication Details: BMC chemistry, Vol.13(1)
Publisher: Springer International Publishing
Identifiers: 9930540108331
Academic Unit: Umm Al Qura University
Language: English
Resource Type: Journal article