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Determination of the relative oxygenation of samples by ortho-positronium 3-gamma decay for future application in oncology
Journal article   Peer reviewed

Determination of the relative oxygenation of samples by ortho-positronium 3-gamma decay for future application in oncology

M. A. Alkhorayef, E. I. Abuelhia, M. P. W. Chin and N. M. Spyrou
Journal of radioanalytical and nuclear chemistry, Vol.281(2), pp.171-174
01/08/2009
DOI: https://doi.org/10.1007/s10967-009-0123-6

Abstract

Chemistry Chemistry, Analytical Chemistry, Inorganic & Nuclear Nuclear Science & Technology Physical Sciences Science & Technology Technology
The exploitation of 3 gamma imaging may open up a new area of interest in medical positron emission tomography (PET) as a new analytical method to detect hypoxic tumour in oncology. The 3 gamma yield was measured in normoxic and hypoxic environments where AnaeroGen (TM) was used to generate the hypoxic environment. The percentage of the coincidence events qualified as 3 gamma was found to be 26.5% higher in the hypoxic environment.

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