Abstract
Two benzofuranoids, deuteromycol A, 6,7-dihydroxy-2-[1′-hydroxy-(1′→5″)-2″,3″,4″-trihydroxy-2″,3″-dihydropyran]benzofuran and deuteromycol B, 1-(6,7-dihydroxy benzofuran-2-yl)methyl acetate have been isolated from the ethanol extract of the marine-derived fungal strain MF 003 (Deuteromycete) obtained from Red Sea mangrove drift wood. Deuteromycols A and B contain a catecholic nucleus that to the best of our knowledge is unusual in association with marine fungi secondary metabolites. Structures were established on the basis of extensive 1D-and 2D-NMR spectroscopic studies as well as on mass spectrometric analysis. Besides, the extracts exhibited
in vitro
antibacterial activity.