Diagnosis and classification of optic neuritis

Axel Petzold; Clare L. Fraser; Mathias Abegg; Raed Alroughani; Daniah Alshowaeir; Regina Alvarenga; Cecile Andris; Nasrin Asgari; Yael Barnett; Roberto Battistella; Raed Behbehani; Thomas Berger; Mukharram M. Bikbov; Damien Biotti; Valerie Biousse; Antonella Boschi; Milan Brazdil; Andrei Brezhnev; Peter A. Calabresi; Monique Cordonnier; Fiona Costello; Franz M. Cruz; Leonardo Provetti Cunha; Smail Daoudi; Romain Deschamps; Jerome de Seze; Ricarda Diem; Masoud Etemadifar; Jose Flores-Rivera; Pedro Fonseca; Jette Frederiksen; Elliot Frohman; Teresa Frohman; Caroline Froment Tilikete; Kazuo Fujihara; Alberto Galvez; Riadh Gouider; Fernando Gracia; Nikolaos Grigoriadis; Jose M. Guajardo; Mario Habek; Marko Hawlina; Elena H. Martinez-Lapiscina; Juzar Hooker; Jyh Yung Hor; William Howlett; Yumin Huang-Link; Zhannat Idrissova; Zsolt Illes; Jasna Jancic; Panitha Jindahra; Dimitrios Karussis; Emilia Kerty; Ho Jin Kim; Wolf Lagreze; Letizia Leocani; Netta Levin; Petra Liskova; Yaou Liu; Youssoufa Maiga; Romain Marignier; Chris McGuigan; Dalia Meira; Harold Merle; Mario L. R. Monteiro; Anand Moodley; Frederico Moura; Silvia Munoz; Sharik Mustafa; Ichiro Nakashima; Susana Noval; Carlos Oehninger; Olufunmilola Ogun; Afekhide Omoti; Lekha Pandit; Friedemann Paul; Gema Rebolleda; Stephen Reddel; Konrad Rejdak; Robert Rejdak; Alfonso J. Rodriguez-Morales; Marie-Benedicte Rougier; Maria Jose Sa; Bernardo Sanchez-Dalmau; Deanna Saylor; Ismail Shatriah; Aksel Siva; Hadas Stiebel-Kalish; Gabriella Szatmary; Linh Ta; Silvia Tenembaum; Huy Tran; Yevgen Trufanov; Vincent van Pesch; An-Guor Wang; Mike P. Wattjes; Ernest Willoughby; Magd Zakaria; Jasmin Zvornicanin; Laura Balcer; Gordon T. Plant

doi:10.1016/S1474-4422(22)00200-9

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Diagnosis and classification of optic neuritis

Journal article

Peer reviewed

Diagnosis and classification of optic neuritis

Axel Petzold, Clare L. Fraser, Mathias Abegg, Raed Alroughani, Daniah Alshowaeir, Regina Alvarenga, Cecile Andris, Nasrin Asgari, Yael Barnett, Roberto Battistella, …

Lancet neurology, Vol.21(12), pp.1120-1134

01/12/2022

DOI: https://doi.org/10.1016/S1474-4422(22)00200-9

PMID: 36179757

Abstract

Clinical Neurology

Life Sciences & Biomedicine

Neurosciences & Neurology

Science & Technology

There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can facilitate the timely treatment of individuals with multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein antibody-associated disease. Epidemiological data show that, cumulatively, optic neuritis is most frequently caused by many conditions other than multiple sclerosis. Worldwide, the cause and management of optic neuritis varies with geographical location, treatment availability, and ethnic background. We have developed diagnostic criteria for optic neuritis and a classification of optic neuritis subgroups. Our diagnostic criteria are based on clinical features that permit a diagnosis of possible optic neuritis; further paraclinical tests, utilising brain, orbital, and retinal imaging, together with antibody and other protein biomarker data, can lead to a diagnosis of definite optic neuritis. Paraclinical tests can also be applied retrospectively on stored samples and historical brain or retinal scans, which will be useful for future validation studies. Our criteria have the potential to reduce the risk of misdiagnosis, provide information on optic neuritis disease course that can guide future treatment trial design, and enable physicians to judge the likelihood of a need for long-term pharmacological management, which might differ according to optic neuritis subgroups.

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Title: Diagnosis and classification of optic neuritis
Creators - without role: Axel Petzold - National Hospital for Neurology and Neurosurgery
Clare L. Fraser - University of Sydney
Mathias Abegg - University of Bern
Raed Alroughani - College Station Medical Center
Daniah Alshowaeir - King Saud University
Regina Alvarenga - Univ Fed Estado Rio de Janeiro UNIRIO, Dept Neurol, Rio De Janeiro, Brazil
Cecile Andris - University of Liège
Nasrin Asgari - University of Southern Denmark
Yael Barnett - St Vincents Hosp, Dept Neuroradiol, Sydney, NSW, Australia
Roberto Battistella - Univ Sao Paulo, Dept Neuroophthalmol, Sao Paulo, Brazil
Raed Behbehani - Sina
Thomas Berger - University of Vienna
Mukharram M. Bikbov - Ufa Eye Research Institute
Damien Biotti - CHU Pierre Paul Riquet Purpan, Unit Neurol Inflammatoire B4, Toulouse, France
Valerie Biousse - Emory University
Antonella Boschi - Pontifícia Universidade Católica de São Paulo
Milan Brazdil - Masaryk University
Andrei Brezhnev - College Station Medical Center
Peter A. Calabresi - Johns Hopkins University
Monique Cordonnier - Univ Libre Bruxelles, Dept Ophthalmol, Brussels, Belgium
Fiona Costello - University of Calgary
Franz M. Cruz - College Station Medical Center
Leonardo Provetti Cunha - Supreme Council Of Health
Smail Daoudi - Univ Mouloud Mammeri Ttizi Ouzou, Dept Neurol, Ttizi Ouzou, Algeria
Romain Deschamps - Hosp Fdn Adolphe Rothschild, Dept Neurol, Paris, France
Jerome de Seze - University of Strasbourg
Ricarda Diem - Heidelberg
Masoud Etemadifar - College Station Medical Center
Jose Flores-Rivera - College Station Medical Center
Pedro Fonseca - University of Coimbra
Jette Frederiksen - University of Copenhagen
Elliot Frohman - Stanford University
Teresa Frohman - Stanford University
Caroline Froment Tilikete - Lyon I Univ, Lyon Neurosci Res Ctr, Lyon, France
Kazuo Fujihara - Supreme Council Of Health
Alberto Galvez - University of Alberta
Riadh Gouider - Razi University
Fernando Gracia - Hosp Santo Tomas, Dept Neurol, Panama City, Panama
Nikolaos Grigoriadis - Aristotle University of Thessaloniki
Jose M. Guajardo - College Station Medical Center
Mario Habek - University of Zagreb
Marko Hawlina - College Station Medical Center
Elena H. Martinez-Lapiscina - Hosp Clin Barcelona, Dept Neurol, Barcelona, Spain
Juzar Hooker - Aga Khan Univ Hosp, Nairobi, Kenya
Jyh Yung Hor - George Institute for Global Health
William Howlett - College Station Medical Center
Yumin Huang-Link - Linköping University
Zhannat Idrissova - Alma
Zsolt Illes - Odense Univ Hosp, Dept Neurol, Odense, Denmark
Jasna Jancic - University of Belgrade
Panitha Jindahra - Mahidol University
Dimitrios Karussis - Tel Aviv University
Emilia Kerty - Oslo Univ Hosp, Rikshosp, Dept Neurol, Oslo, Norway
Ho Jin Kim - Natl Canc Ctr, Dept Neurol, Goyang, South Korea
Wolf Lagreze - University of Freiburg
Letizia Leocani - Univ Vita Salute San Raffaele, Inst Expt Neurol INSPE, Sci Inst San Raffaele, Expt Neurophysiol Unit, Milan, Italy
Netta Levin - Hebrew University of Jerusalem
Petra Liskova - Charles University
Yaou Liu - College Station Medical Center
Youssoufa Maiga - Gabriel Toure Univ Hosp, Dept Neurol, Bamako, Mali
Romain Marignier - Hop Neurol & Neurochirurg P Wertheimer, Serv Neurol Sclerose Plaques Pathol Myelin & Neur, Bron, France
Chris McGuigan - Supreme Council Of Health
Dalia Meira - GAIA
Harold Merle - Fondazione Ricerca Traslazionale
Mario L. R. Monteiro - Supreme Council Of Health
Anand Moodley - University of KwaZulu-Natal
Frederico Moura - Inst Paulista Visao, Dept Neuroophthalmol, Higienopolis, Brazil
Silvia Munoz - Hosp Univ Bellvitge, Dept Ophthalmol, Barcelona, Spain
Sharik Mustafa - Prime Healthcare Grp, Dept Neurol, Dubai, U Arab Emirates
Ichiro Nakashima - College Station Medical Center
Susana Noval - Hosp Univ La Paz, Dept Ophthalmol, Madrid, Spain
Carlos Oehninger - Supreme Council Of Health
Olufunmilola Ogun - University of Ibadan
Afekhide Omoti - Univ Benin, Dept Ophthalmol, Benin, Nigeria
Lekha Pandit - Nitte University
Friedemann Paul - College Station Medical Center
Gema Rebolleda - Ramon & Cajal Hosp, Dept Ophthalmol, Madrid, Spain
Stephen Reddel - Sydney Neurol, Sydney, NSW, Australia
Konrad Rejdak - College Station Medical Center
Robert Rejdak - College Station Medical Center
Alfonso J. Rodriguez-Morales - College Station Medical Center
Marie-Benedicte Rougier - Univ Hosp Bordeaux, Dept Ophthalmol, Bordeaux, France
Maria Jose Sa - Univ Fernando Pessoa, Ctr Hosp Univ Sao Joao, Dept Neurol, Porto, Portugal
Bernardo Sanchez-Dalmau - Hosp Clin Barcelona, Dept Ophthalmol, Barcelona, Spain
Deanna Saylor - Johns Hopkins University
Ismail Shatriah - Supreme Council Of Health
Aksel Siva - Istanbul University-Cerrahpaşa
Hadas Stiebel-Kalish - Tel Aviv University
Gabriella Szatmary - University of Mississippi
Linh Ta - Ho Chi Minh City Eye Hosp, Dept Gen Planning, Ho Chi Minh City, Vietnam
Silvia Tenembaum - Natl Paediat Hosp Dr Juan P Garrahan, Dept Neurol, Buenos Aires, DF, Argentina
Huy Tran - Ho Chi Minh City Univ Med & Pharm, Fac Med, Dept Ophthalmol, Ho Chi Minh City, Vietnam
Yevgen Trufanov - Shupyk Natl Healthcare Univ Ukraine, Dept Neurol & Reflexol, Kiev, Ukraine
Vincent van Pesch - Clin Univ St Luc Brussels, Dept Neurol, Brussels, Belgium
An-Guor Wang - University of Taipei
Mike P. Wattjes - Supreme Council Of Health
Ernest Willoughby - Auckland City Hosp, Dept Neurol, Auckland, New Zealand
Magd Zakaria - Ain Shams University
Jasmin Zvornicanin - Univ Clin Ctr Tuzla, Dept Ophthalmol, Tuzla, Bosnia & Herceg
Laura Balcer - New York Univ, Dept Neurol, Grossman Sch Med, New York, NY USA
Gordon T. Plant - UCL Inst Neurol, Fac Brain Sci, Dept Brain Repair & Rehabil, London, England
Publication Details: Lancet neurology, Vol.21(12), pp.1120-1134
Publisher: Elsevier
Number of pages: 15
Grant note: YNT-Schering Fellowship
Identifiers: 9949886808331
Academic Unit: King Saud University
Language: English
Resource Type: Journal article