Abstract
Background: Hepatocellular carcinoma (HCC) is the most common type of primary hepatic neoplasm that mostly occur in a background of chronic liver disease (CLD) and cirrhosis. Hepatic lesion consists of a wide range of neoplasms, both benign and malignant, with distinct histopathological and radiological findings.
Aim: To determine the concordance in histopathological and radiological findings while diagnosing various liver lesions by keeping histopathology as a gold standard.
Study design: Cross-sectional
Place and duration of study: Aznostics Diagnostics Centre, lttefaq Diagnostic Centre and FMH Lahore, Pakistan from 1st January 2015 to 1st June 2017.
Methods: A total of 50 patients of liver lesions diagnosed on CT scan and histopathological findings were included. All the diagnosed patients of liver lesions were included and the pregnant females were excluded.
Results: By comparing CT scan findings with the histopathological findings the sensitivity was 93.75%, specificity was 85.33%, positive predictive value was 90.90% and negative predictive value was 88.23% in differentiating metastatic liver lesions from other types of liver lesions.
Conclusion: CT scan is a useful tool in diagnosing liver lesions. The results indicate that CT scan shows good sensitivity, specificity, positive predictive value, negative predictive value to differentiating the metastatic tumors of liver from other liver lesions.