Abstract
In recent years, synthetic chemists continue to search for new methodologies to access organic molecules of value. Bromine containing molecules persist to yield interesting discoveries when employed in new (and known) transformations. Whilst a plethora of bromine containing compounds exist in the literature at a chemist's disposal for organic synthesis, this minireview will pay close attention to one of the more understudied reagents in comparison, dibromoisocyanuric acid (DBI) (and its closely related mono‐ or tri‐ bromo derivatives). The scope of this minireview looks to explore the most recent implementations of DBI and its derivatives over the period of 2015–2020, looking closely at its uses in organic transformations, employed as a brominating reagent in dye syntheses amongst other applications.
Dibromoisocyanuric acid: This review highlights some of the most recent synthetic advances since 2015 using the brominating/oxidising agent DBI. This reagent has been employed favourably in the synthesis of dyes, pigments and medicinal based fragments. Furthermore, it's analogous mono‐ and tri‐ derivatives (sodium monobromoisocyanurate and tribromoisocyanuric acid) have been employed in a variety of interesting transformations, and as such, have also been examined in this review.