Abstract
Activities of hepatic glucose-6-phosphatase and fructose-1, 6-diphosphatase in fishes were found to increase by feeding diets rich in protein, sucrose and fat, and decrease with glucose feeding. An increase in activity of these 2 enzymes in the liver, when the supply of glucose is curtailed, could be interpreted as a compensatory adaptation of increased gluconeogenesis in response to the stress imposed (glucose feeding).