Abstract
Natural chitosan-based films (CS) were fabricated by changing ingredient corporations between gold nanoparticles (AuNPs), lithium oxide (Li2O), and graphene oxide (GO). A Series of films with different components were obtained. The structural examination is executed by XRD, FTIR, and EDX to analyze crystal structure, chemical bonding, and chemical contents, respectively. The findings illustrated that, the Li2O@CS exhibited the lowest contact angle with 70 ± 4.6°. Scanning Electron Microscopy (SEM) displayd rod-shaped AuNPs with an average length of 0.3 μm and an average width of 90 nm. The refractive index of CS recorded 2.142, while AuNPs/Li2O/GO@CS slightly declined to 2.085. Concerning AuNPs/Li2O/GO@CS, the detected cell viability percentage of normal lung cells among the usage of 156.25 μg/mL is 98.91%, while 9.77 μg/mL achieved 125.78%. Therefore, combining AuNPs, GO and Li2O within the CS matrix results in films of boosted biocompatibility and can be suggested for medical applications.
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•Natural chitosan-based films were fabricated by changing ingredient corporations using Au NPs, Li2O, and GO.•The structural examination is executed by XRD, FT-IR, and EDX analyses.•The refractive index of (CS) hits 2.142, while AuNPs/Li2O/GO@CS shows a slight decline to reach 2.085•Combining Au NPS, GO, and Li2O within the CS matrix results in films of boosted biocompatibility.