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Dihydroxylation of Olefins with Potassium Permanganate Catalyzed by Imidazolium Salt
Journal article   Peer reviewed

Dihydroxylation of Olefins with Potassium Permanganate Catalyzed by Imidazolium Salt

Imran Khan, Zhi-Bin Luo, Anil Valeru, Yin Xu, Bin Liu, Bhavanarushi Sangepu and Ji-Min Xie
Synthesis (Stuttgart), Vol.50(9), pp.1815-1819
02/05/2018

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The development of an efficient and cost-effective cis-dihydroxylation reaction of acrylate derivatives was achieved. The reaction proceeded in acetone with an imidazolium salt as catalyst to furnish the dihydroxylation of olefins at 0-5 degrees C using KMnO4 as the oxidant. This efficient and non-aqueous protocol was highly suitable for the large-scale preparation of cis-dihydroxylated compounds from the corresponding acrylate derivatives in high yields without overoxidation.

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