Sign in
Direct enantiomeric separation of phenglutarimide by chiral high performance liquid chromatography
Journal article   Peer reviewed

Direct enantiomeric separation of phenglutarimide by chiral high performance liquid chromatography

Hassan Aboul-Enien, Soliman Bakr, Paul Nicholls and Saddek Amr Bakr
Journal of liquid chromatography, Vol.17(5), pp.1105-1110
01/03/1994

Abstract

Enatiomeric separation of racemic phenglutarimide (PG) by chiral high performance liquid chromatography is reported using cellulose tris (3,5-dimethylphenyl carbamate) known as Chiralcel OD chiral stationary phase. Maximum resolution (R sub(s)) of 1.26 is obtained for the enantiometers of PG. The method could be applied for preparative scale chromatography and in the assay of PG in biological fluids.

Metrics

1 Record Views

Details