Abstract
Eight samples from infected and susceptible and from non-susceptible snails (Biomphalaria alexandrina) to Schislosoma mansoni infection were used in this study. Snails samples were studied at the genotypic level by RAPD analysis with two arbitrary primers. The genetic distances between samples were measured by the percentage Of unshared bands. The Studied samples separated into two groups according to their DNA fingerprinting. Thus this study has shown that the RAPD markers method has proved useful in discrimination between susceptible and non-susceptible snails of Biomphalaria alexandrina.