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Dissolution and bioavailability of digoxin tablets
Journal article   Peer reviewed

Dissolution and bioavailability of digoxin tablets

E J Fraser, R H Leach, J W Poston, A M Bold, L S Culank and A B Lipede
Journal of pharmacy and pharmacology, Vol.25(12), pp.968-973
12/1973
PMID: 4150301

Abstract

Abstract A dissolution test is described for tablets of digoxin B.P. Dissolution profiles are reported for 11 brands of digoxin tablets available in Gt. Britain in 1972. Good correlations exist between both the area under the serum concentration/time curve from 0–6 h and (1) the amount of digoxin dissolved in 1 h, (2) the reciprocal of the time for 50% dissolution.

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