Does Gender Affect the Outcomes of Myocardial Revascularization for Left-Main Coronary Artery Disease?

Amin Daoulah; Nezar Essam Elsheikh-Mohamed; Nooraldaem Yousif; Ahmad S. Hersi; Ahmad W. Alharbi; Wael Almahmeed; Mohammed Alshehri; Badr Alzahrani; Amr Elfarnawany; Abdulaziz Alasmari; Reda Abuelatta; Turki Al Garni; Mohamed Ajaz Ghani; Haitham Amin; Shahrukh Hashmani; Faisal Omar M Al Nasser; Niranjan Hiremath; Amr A. Arafat; Youssef Elmahrouk; Hameedullah M. Kazim; Wael Refaat; Ehab Selim; Ahmed Jamjoom; Osama El-Sayed; Ziad Dahdouh; Jairam Aithal; Ahmed M. Ibrahim; Abdelmaksoud Elganady; Mohammed A. Qutub; Mohamed N. Alama; Abdulwali Abohasan; Taher Hassan; Mohammed Balghith; Adnan Fathey Hussien; Ibrahim A. M. Abdulhabeeb; Osama Ahmad; Mohamed Ramadan; Abdulrahman H. Alqahtani; Wael Qenawi; Ahmed Shawky; Ahmed A. Ghonim; Ahmed Elmahrouk; Maryam Jameel Naser; Mohammed Abozenah; Abeer M. Shawky; Abdulrahman M. Alqahtani; Ruqayyah Ali Ahmed; Ahmed F. Abdelaziz; Sameer Alhamid; Amir Lotfi

doi:10.1177/00033197231162481

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Does Gender Affect the Outcomes of Myocardial Revascularization for Left-Main Coronary Artery Disease?

Journal article

Peer reviewed

Does Gender Affect the Outcomes of Myocardial Revascularization for Left-Main Coronary Artery Disease?

Amin Daoulah, Nezar Essam Elsheikh-Mohamed, Nooraldaem Yousif, Ahmad S. Hersi, Ahmad W. Alharbi, Wael Almahmeed, Mohammed Alshehri, Badr Alzahrani, Amr Elfarnawany, Abdulaziz Alasmari, …

Angiology, pp.331972311624-33197231162481

11/03/2023

DOI: https://doi.org/10.1177/00033197231162481

PMID: 36905204

Abstract

Currently, gender is not considered in the choice of the revascularization strategy for patients with unprotected left main coronary artery (ULMCA) disease. This study analyzed the effect of gender on the outcomes of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG) in patients with ULMCA disease. Females who had PCI (n = 328) were compared with females who had CABG (n = 132) and PCI in males (n = 894) was compared with CABG (n = 784). Females with CABG had higher overall hospital mortality and major adverse cardiovascular events (MACE) than females with PCI. Male patients with CABG had higher MACE; however, mortality did not differ between males with CABG vs PCI. In female patients, follow-up mortality was significantly higher in CABG patients, and target lesion revascularization was higher in patients with PCI. Male patients had no difference in mortality and MACE between groups; however, MI was higher with CABG, and congestive heart failure was higher with PCI. In conclusion, women with ULMCA disease treated with PCI could have better survival with lower MACE compared with CABG. These differences were not evident in males treated with either CABG or PCI. PCI could be the preferred revascularization strategy in women with ULMCA disease.

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Title: Does Gender Affect the Outcomes of Myocardial Revascularization for Left-Main Coronary Artery Disease?
Creators - without role: Amin Daoulah - King Faisal Specialist Hospital & Research Centre
Nezar Essam Elsheikh-Mohamed - King Faisal Specialist Hospital & Research Centre
Nooraldaem Yousif - Department of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, 144878Kingdom of Bahrain, Manama, Bahrain.
Ahmad S. Hersi - King Saud University
Ahmad W. Alharbi - King Faisal Specialist Hospital & Research Centre
Wael Almahmeed - Cleveland Clinic
Mohammed Alshehri - Armed Forces Hospital
Badr Alzahrani - Prince Sultan University
Amr Elfarnawany - Department of Cardiovascular Medicine, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
Abdulaziz Alasmari - King Faisal Specialist Hospital & Research Centre
Reda Abuelatta - Islamic University of Madinah
Turki Al Garni - Prince Sultan University
Mohamed Ajaz Ghani - Islamic University of Madinah
Haitham Amin - Department of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, 144878Kingdom of Bahrain, Manama, Bahrain.
Shahrukh Hashmani - Cleveland Clinic
Faisal Omar M Al Nasser - Islamic University of Madinah
Niranjan Hiremath - Cleveland Clinic
Amr A. Arafat - Prince Sultan University
Youssef Elmahrouk - Tanta University
Hameedullah M. Kazim - Armed Forces Hospital
Wael Refaat - King Faisal Specialist Hospital & Research Centre
Ehab Selim - Armed Forces Hospital
Ahmed Jamjoom - King Faisal Specialist Hospital & Research Centre
Osama El-Sayed - King Faisal Specialist Hospital & Research Centre
Ziad Dahdouh - King Faisal Specialist Hospital & Research Centre
Jairam Aithal - Shaikh Khalifa Medical City
Ahmed M. Ibrahim - King Fahad Hospital Jeddah
Abdelmaksoud Elganady - Department of Cardiology, 124911Dr Erfan and Bagedo General Hospital, Jeddah, Saudi Arabia.
Mohammed A. Qutub - King Abdulaziz University
Mohamed N. Alama - King Abdulaziz University
Abdulwali Abohasan - Saud Al-babtain Cardiac Centre
Taher Hassan - Department of Cardiology, 48131Bugshan General Hospital, Jeddah, Saudi Arabia.
Mohammed Balghith - King Saud bin Abdulaziz University for Health Sciences
Adnan Fathey Hussien - King Abdullah International Medical Research Center
Ibrahim A. M. Abdulhabeeb - King Abdulaziz Hospital
Osama Ahmad - King Faisal Specialist Hospital & Research Centre
Mohamed Ramadan - King Faisal Specialist Hospital & Research Centre
Abdulrahman H. Alqahtani - King Abdulaziz Medical City
Wael Qenawi - Armed Forces Hospital
Ahmed Shawky - Armed Forces Hospital
Ahmed A. Ghonim - Department of Cardiology, 204603Prince Sultan Cardiac Center Al Hassa, Hofuf, Saudi Arabia.
Ahmed Elmahrouk - Tanta University
Maryam Jameel Naser - Baystate Medical Center
Mohammed Abozenah - Baystate Medical Center
Abeer M. Shawky - Department of Cardiology, 124911Dr Erfan and Bagedo General Hospital, Jeddah, Saudi Arabia.
Abdulrahman M. Alqahtani - King Fahd Medical City
Ruqayyah Ali Ahmed - 204586Batterjee Medical College, Jeddah, Saudi Arabia.
Ahmed F. Abdelaziz - Soliman Fakeeh Hospital
Sameer Alhamid - King Fahd Medical City
Amir Lotfi - Baystate Medical Center
Publication Details: Angiology, pp.331972311624-33197231162481
Identifiers: 9913011008331
Academic Unit: Al Jouf University; King Abdulaziz University; King Saud University; King Saud Bin Abdulaziz University for Health Sciences
Language: English
Resource Type: Journal article