Abstract
Phytochemical investigations of Suaeda fruticosa resulted in the isolation of two new dopamine-derived amides: N-(4-hydoxy-3-methoxyphenylethyl)-hexacosanamide (1) and N-(4-hydoxy-3-methoxyphenylethyl)-tetracosanamide (2), along with five known tyramine-derived amides: N-(4-hydroxyphenethyl)-hexacosanamide (3), N-(4-hydroxyphenethyl)-octacosanamide (4), tetracosunoyltyrumine (5), N-docosanoyltyrumine (6), and crotamide B (7). Their structures were elucidated due to the combination of various spectroscopic data including 1D- and 2D-NMR techniques and high resolution mass spectrometry. All the isolates (1-7) were tested and found to be inactive against a-glucosidase, acetylcholinesterase, butyrylcholineste, lipoxygenase and DPPH free radical.