Abstract
Aim: To identify the drug resistance phenotypes of clinical Ps. aeruginosa isolates from various clinical samples in Khartoum state, Sudan.
Methods: This cross-sectional study was carried out during October 2016 up to April 2018. Conventional microbiological tests used for isolation and identification of this organism and Kirby-Bauer disc diffusion technique used to determining antimicrobial resistance patterns.
Results: Out of 150 clinical specimens, 37 (24.7%) were positive for Ps. aeruginosa. Sixteen Ps. aeruginosa strains (43.24%) were isolated from ear swabs, followed by 15 (41%) from wounds, 3 (8%) from urine, 2 (5%) from sputum and 1 (3%) from eye swabs. Ps. aeruginosa isolates were found high resistance to piperacillin (78.4%), followed by cefepime (56.7%), aztreonam (43.2%), ceftazidime (40.5%), gentamicin (18.9%), ciprofloxacin (16.2%) and amikacin (13.5%). However, the isolates were shown low resistance rate to imipenem (8%). Interestingly, we observed that 40.5% of Ps. aeruginosa strains were multi-drug resistance.
Conclusion: This study concludes that Ps. aeruginosa were resistance to all prescribed anti-pseudomonal drugs and roughly, half of the clinical isolates are multidrug resistance.