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Dynamic resolution of N-Boc-2-lithiopiperidine
Journal article   Peer reviewed

Dynamic resolution of N-Boc-2-lithiopiperidine

Iain Coldham, Sophie Raimbault, Praful T. Chovatia, Jignesh J. Patel, Daniele Leonori, Nadeem S. Sheikh and David T. E. Whittaker
Chemical communications (Cambridge, England), (35), pp.4174-4176
01/01/2008
PMID: 18802520

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Dynamic thermodynamic resolution of N-Boc-2-lithiopiperidine is possible using a chiral ligand; the two enantiomers of this organolithium can be resolved with selectivities of up to 85 : 15 from a selection of 26 chiral diamino-alkoxide ligands screened.

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