Abstract
Objective: To find out various Echocardiographic findings in patients with HOCM.
Methodology: This was a retrospective cross-sectional study performed in Cardiology department Lady Reading Hospital, Peshawar. Data collected from the database computer section of echocardiography department from February 2009 to November 2011. The data was analyzed using SPSS version 14.
Results: Total study population was 28. Male were 14 (50%). Mean age was 52.5 +/- 15.9 years. Mean left ventricular end diastolic dimension was 3.84cm; inter-ventricular septal thickness 2cm (1.1-3.1) and posterior wall thickness was 1.17cm (0.6-1.6). Mean Left atrial (LA) diameter was 3.86cm (0.8-5.6). Mean peak gradient across LVOT was 48.43 mmHg. Mitral regurgitation (MR) was found in 19 (67.9%) patients. MR was mild in 57.1%, moderate in 7.1% and severe in 3.6% of patients. Aortic regurgitation (AR) was found in 13 (46.4 %) patients. AR was mild in 35.7%, moderate in 10.7% of patients. Left atrial size was increased in 14 (50%) patients. Mean LA diameter was 4.6cm, 5cm and 5.6cm in patients with mild, moderate, and severe MR respectively. So there was direct relation between severity of MR and LA diameter. The respective mean gradient across LVOT in patients mild, moderate and severe MR was 31mmHg, 43.5mmHg and 140mmHg. So higher the gradient across LVOT, more will be the MR and hence the LA size and the patient will be more symptomatic.
Conclusion: HOCM is significantly associated with both MR and AR and there is direct relation between severity of MR with LA diameter and LVOT gradient.