Abstract
Migraine headache is considered to be a common and complex neurovascular disorder with a characteristic of recurrent episodes. It affects one side of the head (unilateral) and it is associated with other symptoms including, nausea, vomiting, photophobia, tiredness, neck stiffens, and throbbing pain that increase with movement. Types of migraine are migraine with aura, migraine without aura, retinal migraine, and chronic migraine. Choosing the best and the most effective treatment for migraine are based on diagnosis according to different criteria and migraine phase. The treatment is classified into two categories; treatment that stops the headache from progressing including nonsteroidal anti-inflammatory drugs (NSAIDs), selective serotonin receptor agonists (triptans) and analgesics and the other one is prophylactic treatment that prevents headache onset such as tricyclic antidepressants, calcium channel blockers, beta-blockers and antiepileptic drugs. Chronic migraine (CM) has different lines of treatment: invasive, oral prophylactic agents, and Botox.