Abstract
In this study four groups of chicken challenged with Clostridium perfringens were fed on Neoxyval, GalliPro, TechnoMos and GalliPro + TechnoMos. A group fed on normal diet was used as control and the other challenged with bacterium was maintained. Three hepatic enzymes viz., lactate dehydrogenase (LDH), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) increased after feeding on growth promoters. However, total serum protein, gamma glutamyl transferase (GGT) and alkaline phosphatase (ALP) showed no significant differences between the groups. Thus, it can be concluded that probiotic, prebiotic and symbiotic in feed may cause some degree of liver damage as indicated by the release of AST and ALT in the serum.