Abstract
Plants and plant parts are being utilized for drug discovery and development in recent years. Out of the flora from Arabic peninsula, Fagonia arabica is claimed to have many medicinal properties. Current project was undertaken to assess the anti-hepatotoxic efficacy associated with Fagonia arabica dry leaves powder against acetaminophen induced hepatotoxicity. Single hepatotoxic dose of acetaminophen at a concentration of 1000mg/kg BW was given to induce the hepatotoxicity. The same time, two different concentrations of 250 mg/Kg BW, and 500 mg/kg BW of Fagonia arabica dried leaf powder were used to assess possible hepatocyte protection.. Evaluation was carried with help of liver and kidney function tests and liver histopathology.