Abstract
Many extrinsic and intrinsic etiological factors are responsible for cellular injury. Radiation is a harmful etiological factor for cellular injury by producing free radicals. During cellular metabolism free radicals are produced and neutralised by anti-free radicals. Radiation causes imbalance between it thus leading to cellular injuries and changes accordingly. Olive leaves may play protective role to cells against injury. Histomorphological study establishes the role of it as a protective nature. The aim is to study histomorphological changes in radiation induced injury of liver cells treated with olive leaves and to its protective role in albino male rats. Thirty male albino rats with an average weight 100-110 grams. The rats were divided equally into three groups that included control group without any treatment for one month. Group 2 irradiated by exposing to 6 Gy (fractional dose 2Gy each 3 days). Group 3 were irradiated as group 2 and treated orally with olive leaves extracts with a dose of 1ml/100gm of body weight every day for one month. The morphological and histological structures of the liver were compared in different groups of the rats.Significant changes of cellular injury were observed in group 2 as compared with control group. Group3 showed obvious decrease in pathological changes compared with group 2. These results indicate protective role of olive leaves against radiation induced injury in liver.