Abstract
Many external factors can affect hormonal level including physical activity and altitude level. Vitamin D (25(OH)D) and parathyroid hormone (PTH) hormone have critical role in regulation of many physiological and metabolic processes. 25(OH)D and PTH deficiencies usually treated by synesthetic substitutes which may have adverse effects. This study aimed to investigate the effect of selected exercise program on the regulation of these hormones. Forty females of high altitude residents and twenty females of low altitude residents participated in this study with age of 20-25 years. High altitude residents were randomly assigned into two groups (GI and GII) each contain 20 subjects. GI received the selected exercises for three months. GII didn't participate in the exercise program. GIII was the 20 low altitude residents and didn't participate in the exercise program. Serum level of the hormones was measured for all groups at the beginning and at the end of the study. Three-way mixed MANOVA revealed significant increase in 25(OH)D level after the exercise program in GI while PTH showed non-significant decrease after exercise. The difference between the hormonal levels at high and low altitude was non-significant. We concluded that skeletal muscles and muscular activities play an important role in vitamin D metabolism.