Abstract
Autologous platelet-rich plasma (PRP) can be a valid agent that is effective in inducing and accelerating bone healing for the treatment of periodontal defects and also to accelerate alveolar bone regeneration. Early healing appeared to be impaired by the presence of microfibrillar collagen (MFC) and impeded by the presence of oxidized regenerated cellulose (ORC). In contrast, alkylene oxide copolymer (AOC) did not inhibit bone healing and suggest that AOC may be a better bone hemostatic material for procedures where bony fusion is critical and immediate hemostasis required.