Abstract
The aim of this study was to investigate the effects of daily oral feeding 8% and 15% of powdered leaves of Murraya koenigii leaves (MKL) (commonly knoun as curry) and Brassica juncea seeds (BJS) (commonly knoun as mustard) for 45 days on serum glucose concentration, serum lipids, liver and kidney functions in diabetic rats. A total of 36 adult male albino rats (Sprague Dawley strain) weighting 159 square 2.4g each were used in this investigation. Non-diabetic control (-) (6 rats) were fed basal diet,while diabetic control (+) main group (30) rats divided into five groups after injected with alloxan (150mg/kg), at the end of the experiment, weight gain was calculated. Liver of each rat were removed rapidly then weighted separately. Blood samples were used for estimation of fasting serum glucose, ALT, AST, ALP, triglycerides, total cholesterol, high density lipoprotein (HDLc), low density lipoprotein (LDLc), very low density lipoprotein (VLDLc). Data showed that serum AST and ALT levels declined significantly (p< 0.05) in all treated groups fed on 7% and 15% curry and mustard compared with diabetic positive control. Moreover, both spices resulted in reduction of serum total cholesterol and LDLc + VLDLc a companied with an increase in the HDLc and significantly lowering of serum glucose levels. Thus, these plants can be best utilized by promoting them as preferable food for diabetic patients.