Abstract
Effects of a single intramuscular depot-corticosteroid in allergic rhinitis were studied at clinical and light microscopic levels in Saudi personnel with allergic rhinitis. Clinical studies and biopsies were performed before and after treatment. Following a single intramuscular injection of Depo-Medrol all patients experienced relief and remained symptom-free thereafter for several months. The roentgenographic appearance of the sinuses, eosinophilia of blood and nasal secretion, skin reactivity and the microscopic features exhibited improvement. These findings suggest that a single intramuscular injection of Depo-Medrol is a satisfactory agent for the treatment of allergic rhinitis.