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Efficient Pd(ii)-catalyzed regioselective ortho-halogenation of arylcyanamides
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Efficient Pd(ii)-catalyzed regioselective ortho-halogenation of arylcyanamides

S. N. Murthy Boddapati, Ramana Tamminana, M. Mujahid Alam, Sailaja Gugulothu, Ravi Varala and Hari Babu Bollikolla
New journal of chemistry, Vol.45(37), pp.17176-17182
07/10/2021

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Regioselective ortho-halogenation of arylcyanamides using a Pd(ii) catalyst has been established under mild reaction conditions. Either electron-donating or electron-withdrawing groups readily carried out the reaction and produced final products in moderate to good yields. Based on the experimental work, we have confirmed that this method does not undergo a free radical mechanism. Furthermore, we have also attempted this method for practical utility purposes.

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