Abstract
In this project, we presented a new method for synthesis of multi-walled carbon nanotube-supported platinum-tungsten alloy nanoparticles (Pt-W/MWCNTs) by facile one-step alcohol-reduction process. The synthesized Pt-W/MWCNTs composites were characterized using X-ray diffraction (XRD), transmission electronic microscopy (TEM) and Field-emission scanning electron microscope (FE- SEM). To consider the catalytic efficiency of Pt-W/MWCNTs composites, the electro-oxidation of cefixime antibiotic using the Pt-W/MWCNTs composites on glassy carbon electrode (Pt- W/MWCNTs/GCE) was tested in buffer solution (pH 7.0) using linear sweep voltammetry (LSV) and cyclic voltammetry (CV). Bare GCE demonstrates a passive oxidation wave around 1.02 V for cefixime antibiotic whereas Pt-W/MWCNTs/GCE demonstrates an apparent oxidation peak at 0.66 V. The modified electrode does not indicate any fouling effect toward the oxidation of cefixime antibiotic. To describe the electrode modifying process, electrochemical impedance spectroscopy (EIS) was used. The amperometry method was applied to distinguish cefixime antibiotic in the concentration range of 1.0 × 10 -8 to 3.2 × 10 -6M with a detection limit of 5 × 10-9 M.