Abstract
A core-shell nanocomposite (GO/Fe3O4@SiO2 in this case) and ionic liquid have been used to improve the sensory properties of carbon paste electrode (CPE) entitle GO/Fe3O4@SiO2/IL-CPE as new analytical approach. We validated the applications of GO/Fe3O4@SiO2/IL-CPE for the determination of sulfasalazine by using different electrochemical techniques. Under the optimized experimental condition, the linearity range and the detection limit (LOD) of GO/Fe3O4@SiO2/IL-CPE were 1.0-300.0 and 0.4 mu M for sulfasalazine, respectively. The recording data showed that GO/Fe3O4@SiO2/IL-CPE could be fabricated easily fabricated with outstanding stability. The sensor was applied to the detection of drug in real samples.