A formal synthesis of eurylene is described, where both cis- and trans-THF-containing fragments were prepared using diastereo- and chemoselective permanganate-mediated oxidative monocyclizations of trienes.
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Title
Enantioselective Formal Synthesis of Eurylene: Synthesis of the cis- and trans-THF Fragments Using Oxidative Cyclization
Creators - without role
Nadeem S. Sheikh - University of Southampton
Carole J. Bataille - University of Southampton
Tim J. Luker - University of Southampton
Richard C. D. Brown - University of Southampton
Publication Details
Organic letters, Vol.12(11), pp.2468-2471
Publisher
Amer Chemical Soc
Number of pages
4
Grant note
AstraZeneca
Royal Society
University of Southampton