Abstract
Well-crystallized flower-shaped copper oxide nanostructures composed of thin nanosheets has been synthesized by simple low-temperature hydrothermal process and used to fabricate highly sensitive amperometric glucose biosensor which exhibited a high and reproducible sensitivity of 47.19
μA
mM
−1
cm
−2, response time less than 5
s, linear dynamic range from 0.01 to 10.0
mM, correlation coefficient of
R
=
0.9986, and limit of detection (LOD), based on S/N ratio (S/N
=
3) of 1.37
μM. This work opens a way to utilize simply-grown CuO nanostructures as an efficient electron mediator to fabricate efficient glucose biosensors.