Abstract
Different eye signs or symptoms seen in primary health care clinics and emergency departments may indicate the urgency for advanced and specialized care from ophthalmologists. Eye pain is one of the commonest complains encountered in various age groups and for that it is essential for health care providers to be aware of alarming features of eye pain and how to deal with it plus knowing when referral to an ophthalmologist is indicated. In many cases, isolated pain with no other signs and clear examination may lead to underestimation or misdiagnose of critical situation in which vision-saving can be a matter of time. Subsequently, this review article is provided to primary health care physicians and non-specialized caregivers who might face similar cases. In this review, differential diagnosis of pain in clear quiet eyes have been discussed briefly pointing out most relevant history and examination points, risk factors, treatment options and expected outcomes or prognosis of each differential.